Tums Overdose: Warning Signs You Should Never Ignore

Omid Mehrpour
Post on 02 Oct 2025 . 12 min read.
Omid Mehrpour
Post on 02 Oct 2025 . 12 min read.
People often underestimate how easily a Tums overdose can happen. Many of us believe these common antacids are harmless. The reality shows that taking more than the recommended amount of calcium carbonate can lead to serious health issues. Follow the 24-hour maximum for your product strength: Regular, 500 mg (up to 15 tablets/day), Extra Strength, 750 mg (up to 10 tablets/day), or Ultra, 1000 mg (up to 7 tablets/day). Don’t use the maximum dose for more than two weeks unless advised to do so by a clinician. This corresponds to Regular 500 mg (≤15/day), Extra 750 mg (≤10/day), or Ultra 1000 mg (≤7/day) within a 24-hour period.
The question "Can you overdose on Tums?" has a clear answer - yes. Taking too many Tums causes worrying symptoms. These range from constipation and nausea to irregular heartbeat. Severe cases might even lead to coma. Calcium-carbonate overdose can cause nausea, constipation, decreased appetite, confusion, weakness, and—in severe cases—abnormal heart rhythms. Decreased reflexes or slowed breathing are more typical of magnesium-containing antacids, not calcium carbonate alone. The body's calcium and acid balance faces disruption when large amounts of calcium carbonate-containing antacids enter the system. This can damage the kidneys. Though death from antacid overdose rarely occurs and most people recover well, the risks remain serious. Let's learn about the warning signs of a Tums overdose you should never ignore and the steps to take if you suspect an overdose.
A Tums overdose occurs when someone takes more calcium carbonate than their body can process safely. The body's systems struggle to handle excessive amounts of calcium and alkali compounds that exceed the recommended dosage on the product label.
Tums' active ingredient, calcium carbonate, rapidly neutralizes stomach acid [1]. The medication dissolves in your stomach and begins to neutralize hydrochloric acid, thereby raising the pH level of your stomach contents [2]. This neutralization relieves symptoms of heartburn, acid indigestion, and sour stomach [1]. Raising gastric pH above ~4 reduces pepsin activity, which can further ease symptoms [3]. Some data suggest calcium may aid esophageal clearance, but this effect is inconsistent and not a primary reason to use Tums [4].
Several factors cause people to exceed the recommended Tums dosage:
Severe heartburn that doesn't respond to regular doses
A wrong assumption that "over-the-counter" medications are safe in any amount
Chronic digestive issues without proper medical consultation
Double usage as both a calcium supplement and heartburn relief
In North America, about 18–28% report weekly reflux symptoms; daily symptoms are much less common (~2–10%) [4]. These systemic problems lead many people to reach for Tums repeatedly, often exceeding safe limits.
Tums overdose is a real possibility. Calcium carbonate can be dangerous in large quantities [3]. The product label warns users against exceeding recommended doses [1]. Large amounts can trigger milk-alkali syndrome, a serious condition that causes high blood calcium levels and potential kidney damage [5].
Long-term excessive calcium and antacid intake create risks that most people overlook. The symptoms include loss of appetite, stomach pain, and an increased risk of kidney stones or kidney damage [5]. Calcium carbonate might not be highly toxic, and antacid overdose deaths are rare [3]. Yet the effects on your kidney function and heart rhythm can become serious over time.
Knowing the warning signs of a Tums overdose is vital to getting help quickly. The symptoms worsen over time, and early detection can help prevent serious health issues.
The first signs of a Tums overdose might seem like minor discomfort. Constipation is one of the most common symptoms, especially when you have calcium-containing antacids [6]. This problem persists as long as someone continues to take excessive amounts of antacids. People may also notice dry mouth, especially if dehydration develops [7]. Nausea and vomiting can happen too, and many people think these come from their stomach problems rather than the antacid [8]. Your appetite might drop as calcium builds up in your body [9].
The symptoms become increasingly severe over time. Progression can bring muscle weakness and fatigue (from electrolyte shifts); true twitching is less typical for calcium carbonate and is seen more with magnesium-containing antacids [6]. These muscle problems occur due to changes in your blood's calcium, magnesium, and phosphorus levels. People may feel confused or struggle to think clearly [3]. Headaches and irritability are common, too [9]. Changes in mental state show that extra calcium affects brain function [8]. Depression and increased thirst should not be ignored [9].
Too many Tums can lead to dangerous complications if left untreated. An irregular heartbeat is one of the most serious warning signs [7]. You might feel your heart pounding or racing [9]. Hypercalcemia is typically defined as a serum calcium level greater than 10.5 mg/dL; serious complications, such as arrhythmias or coma, are more likely at higher levels (often exceeding 14 mg/dL) [10]. Other red-flag signs include worsening confusion, severe dehydration, vomiting, or fainting—seek emergency care if any occur [7].
Tums overdose looks a lot like calcium overdose because calcium carbonate is the main ingredient. Because Tums are calcium carbonate, gastrointestinal effects like constipation or gas can occur—similar to other calcium-carbonate products. Milk-alkali syndrome, which involves high calcium levels, an alkaline pH, and kidney problems, is a specific risk associated with calcium carbonate antacids [6]. Without treatment, milk-alkali syndrome can injure the kidneys (nephrocalcinosis/AKI) and may cause ectopic calcifications [6].
Quick action is vital if you suspect someone has taken too many Tums. The steps you take next could make a significant difference in how well the treatment works.
You should call 911 without delay if someone shows serious symptoms like difficulty breathing, seizures, or unconsciousness after a Tums overdose [11]. The situation might seem less severe, but you should still contact Poison Control at 1-800-222-1222 [3]. This national hotline serves callers anywhere in the United States. Stay calm. Do not try to make the person vomit unless a poison control specialist or healthcare provider tells you to do so [7]. If they can swallow safely, offer small sips of water. Do not induce vomiting unless Poison Control or a clinician instructs you [12].
Emergency responders need specific details to help effectively. Be ready to tell them:
The person's age, weight, and current condition
The exact product name (Tums) and its ingredients (calcium carbonate)
The time the medication was swallowed
The number of tablets taken [3]
The Tums container should accompany you to the hospital, as it contains vital information about the strength and ingredients [7].
The toll-free Poison Help hotline connects you with toxicology experts who offer confidential guidance [11]. These centers operate continuously, 24 hours a day, 365 days a year [13]. The specialists assess each situation and determine its severity. They may suggest monitoring at home for mild cases or seeking immediate medical attention for severe ones. Remember, you don't need to wait for an emergency to call - they welcome questions about any poison-related concerns [7].
Regular overuse of Tums can lead to serious long-term health risks that develop gradually without warning signs.
Too much calcium from Tums can substantially affect your kidney health. Over time, supplemental calcium may raise kidney-stone risk—especially when taken between meals [1]. Calcium supplements (including high-dose calcium-carbonate antacids) can increase urinary calcium excretion, elevating stone risk [1]. Chronic overuse can precipitate milk-alkali syndrome, causing acute kidney injury and, if unrecognized, potential chronic impairment [14]. Kidney injury from milk-alkali syndrome can be insidious; laboratory tests often show elevated calcium and bicarbonate levels before symptoms are apparent [15]. Excessive supplemental calcium and prolonged high-dose calcium-carbonate antacid use can increase the risk of kidney stones and cause milk-alkali syndrome, which stresses the kidneys. These risks are distinct from proton pump inhibitor (PPI) kidney findings [15].
Your heart's normal function can be seriously disrupted by high blood calcium levels caused by excessive Tums use. Hypercalcemia (serum calcium exceeding 10.5mg/dL) alters your heart's electrical activity and can lead to dangerous arrhythmias [10]. Severe hypercalcemia can alter cardiac conduction and trigger arrhythmias; case reports show EKG changes that can mimic a heart attack [16]. A notable case shows a patient's EKG abnormalities from too much Tums actually looked like a heart attack [10].
Related topic: [What happens if you deliberately overdose on vitamin D?]
Milk-alkali syndrome accounts for >10% of hypercalcemia cases and is the third most common cause in hospitalized patients [5]. This dangerous condition is characterized by high calcium levels, metabolic alkalosis, and kidney impairment [17]. The name originates from historical milk-based treatments for ulcers, but today, most cases are attributed to calcium-containing antacids, such as Tums [18]. Milk-alkali syndrome most often occurs with higher calcium intakes (commonly >4 g/day), but cases at 1–2 g/day can occur—especially with CKD, thiazide diuretics, or vitamin D [19].
Related Blog: Can you overdose on vitamin D?
If you’re using Tums daily for >2 weeks or need the maximum dose, stop self-treating and see a clinician to evaluate the cause [20]. Watch out for warning signs, such as worsening heartburn despite medication, trouble swallowing, unexplained weight loss, or a chronic cough [20]. Medical attention becomes urgent if you experience severe stomach pain or vomiting, particularly with blood present [20]. No over-the-counter medication comes without risks [14]. A 24-hour urine evaluation is especially useful for individuals with recurrent or high-risk stone formation to personalize prevention[1].
Tums looks like a safe over-the-counter fix for heartburn, but taking too much can be dangerous. Death from Tums overdose rarely happens, but the potential risks are real. Most people don't know that these common antacids contain calcium carbonate, which throws off your body's chemical balance when you take too much.
The warning signs start with mild issues like constipation and nausea before getting worse with confusion and muscle twitching. Your heart rhythm could become irregular in severe cases, and you might even fall into a coma. The most important thing to do if you suspect an overdose is to call poison control right away at 1-800-222-1222. They'll tell you exactly what to do.
Taking too many Tums over time is just as risky. You could end up with kidney stones, permanent kidney damage, irregular heartbeats, or milk-alkali syndrome. These medications help when used correctly, but can harm you if you're not careful.
Frequent heartburn that requires you to reach for antacids needs a doctor's attention, rather than self-treatment. Your doctor will find out why it happens and suggest better treatments than just masking the symptoms. Tums helps with occasional acid discomfort, but following the recommended doses keeps you safe from the serious complications we discussed in this piece.
Understanding the risks of Tums overdose can protect you from serious health complications that many people don't realize exist with this common over-the-counter medication.
• Tums overdose is real and dangerous - Exceeding the 24-hour labeled maximum for your tablet strength (Regular 500 mg ≤15/day, Extra 750 mg ≤10/day, Ultra 1000 mg ≤7/day) increases overdose risk.
• Watch for progressive warning signs - Mild symptoms like constipation and dry mouth can escalate to confusion, muscle twitching, and dangerous heart rhythm problems.
• Call Poison Control immediately - Contact 1-800-222-1222 for professional guidance if overdose is suspected; don't wait for severe symptoms to develop.
• Long-term overuse damages the kidneys and heart - Regular excessive use can cause kidney stones, permanent kidney damage, and milk-alkali syndrome.
• Stop self-medicating after two weeks - Daily Tums use beyond two weeks requires medical evaluation to address underlying digestive issues safely.
While Tums provides effective relief for occasional heartburn, treating it with the same respect as any medication—following dosage guidelines and seeking medical attention for persistent symptoms—prevents potentially serious health consequences that can develop silently over time.
Symptoms can range from mild to severe. Early signs include nausea, constipation, and dry mouth. More serious symptoms may involve confusion, muscle twitching, irregular heartbeat, and in extreme cases, even coma.
Don’t exceed the 24-hour maximum for your product: Regular 500 mg ≤15/day, Extra 750 mg ≤10/day, Ultra 1000 mg ≤7/day. Going beyond these limits raises overdose risk. Depending on the dosage, this can be anywhere from 7 to 15 Tums tablets.
If you suspect a Tums overdose, contact Poison Control immediately at 1-800-222-1222. For severe symptoms, such as difficulty breathing or unconsciousness, call 911 immediately.
Yes, frequent overuse of Tums can lead to serious health issues such as kidney damage, kidney stones, heart rhythm problems, and a condition called milk-alkali syndrome.
If you've been using Tums daily for more than two weeks, it's time to stop and consult a doctor. Also seek medical attention if you experience worsening heartburn, difficulty swallowing, unexplained weight loss, or chronic cough despite taking Tums.
© All copyright of this material is absolute to Medical toxicology
Dr. Omid Mehrpour (MD, FACMT) is a senior medical toxicologist and physician-scientist with over 15 years of clinical and academic experience in emergency medicine and toxicology. He founded Medical Toxicology LLC in Arizona and created several AI-powered tools designed to advance poisoning diagnosis, clinical decision-making, and public health education. Dr. Mehrpour has authored over 250 peer-reviewed publications and is ranked among the top 2% of scientists worldwide. He serves as an associate editor for several leading toxicology journals and holds multiple U.S. patents for AI-based diagnostic systems in toxicology. His work brings together cutting-edge research, digital innovation, and global health advocacy to transform the future of medical toxicology.
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[2] - https://go.drugbank.com/drugs/DB06724
[3] - https://www.mountsinai.org/health-library/poison/calcium-carbonate-overdose
[4] - https://www.ncbi.nlm.nih.gov/books/NBK526049/
[5] - https://pmc.ncbi.nlm.nih.gov/articles/PMC7238301/
[6] - https://www.prevention.com/health/a20516891/too-many-antacids-side-effects/
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[11] - https://www.poison.org/
[12] - https://www.poisonhelp.org/
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[14] - https://www.uhhospitals.org/blog/articles/2024/03/is-the-long-term-use-of-antacids-safe
[15] - https://medicine.washu.edu/news/popular-heartburn-drugs-linked-gradual-yet-silent-kidney-damage/
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[17] - https://pmc.ncbi.nlm.nih.gov/articles/PMC3546438/
[18] - https://www.mja.com.au/journal/2005/182/7/life-threatening-milk-alkali-syndrome-resulting-antacid-ingestion-during
[19] - https://pmc.ncbi.nlm.nih.gov/articles/PMC6215939/
[20] - https://www.webmd.com/heartburn-gerd/when-call-doctor