

ToxiCOWS is an interactive, evidence-based tool that guides clinicians step-by-step through the Clinical Opioid Withdrawal Scale (COWS), instantly calculates a score, and provides severity-based, personalized treatment recommendations to improve care.


• About
Opioid Withdrawal Scoring
Quickly assess withdrawal severity using the Clinical Opioid Withdrawal Scale (COWS).
Buprenorphine Readiness
Supports treatment decisions by interpreting COWS thresholds for medication initiation.
Live Score & Category
Auto-calculates total score with real-time classification (mild to severe).
No Login Required
Instant use—no account or setup needed.
Free & Mobile-Friendly
Browser-based and fully responsive on any device.
• Changelog
• Initial release of the product
• FAQ
ToxiCOW is designed for clinicians, toxicologists, emergency providers, addiction specialists, and pharmacists managing opioid withdrawal in hospital, ED, or outpatient settings.
You’ll need clinical observations related to the 11 COWS items, including vitals, pupil size, tremor, yawning, and GI symptoms.
ToxiCOW suggests academically accepted treatment options based on COWS scores, such as thresholds for buprenorphine initiation. However, final decisions must be made by the provider using clinical judgment.
ToxiCOW is based on standard COWS scoring and best used for acute opioid withdrawal. It may not be accurate for complex polysubstance cases or chronic pain patients with atypical presentations.
• Privacy Policy
We respect your privacy; this section explains what information we collect, how we use it, and how we protect its security.
Read Privacy Policy• Terms and Conditions
This section outlines the rules, obligations, and rights that apply when you use our website or services.
Read Terms and Conditions